Sequencing

In genetics and biochemistry, sequencing means to determine the primary structure (or primary sequence) of an unbranched biopolymer. Sequencing results in a symbolic linear depiction known as a sequence which succinctly summarizes much of the atomic-level structure of the sequenced molecule. In genetics terminology, sequencing is most often restricted to determining the nucleotides of a DNA or RNA strand. Methods to perform DNA or RNA sequencing include:\n* chromosome walking\n* shotgun sequencing\n* Chain termination method Future methods:\n* nanopore sequencing\n* GeneEngine Methods for performing protein sequencing\ninclude:\n*Edman degradation\n*mass spectrometry\n*protease digests \nThough polysaccharides are biopolymers, it is not so common to talk of\nsequencing a polysaccharide, because a symbolic linear depiction cannot\ncapture their tendency to branch and to bond to one other\nin different ways.

See also

\n* Genetic code\n* Sequence motif

External links

\n*Information on genome projects, and the data they have produced at the National Center for Biotechnology Information\nCategory:Molecular biology\n\n